Depression and Inflammation

Now that I know what inflammation is and have given you my personal view of depression, I can talk about depression as an inflammatory disease.  Most specifically, the article “So depression is an inflammatory disease, but where does the inflammation come from?” from BiomedCentral Medicine.  I’ll do some additional research as warranted, but mostly I want … Continue reading “Depression and Inflammation”

Chronic and Systemic Inflammation

If I’m reading this correctly, there is no bright line between acute and chronic inflammation.  Chronic inflammation is acute inflammation that didn’t go away.  Over time this may lead to accumulated effects, and the distribution of mediators and their sources may shift, but there’s a lot overlap. There’s a few ways chronic inflammation can hurt … Continue reading “Chronic and Systemic Inflammation”

I wanted to talk about depression but first I have to talk about inflammation

Monday’s post was inspired by this paper on depression and inflammation.  Let’s dig in. First question:  what is inflammation?  Allow me to translate the wikipedia article. First, local cells detect that something is there that should not be.  Not every cell can do this.  Wiki’s list is:  macrophages, dendritic cells, histiocytes, Kupffer cells and mastocytes.  Every cell on that list is … Continue reading “I wanted to talk about depression but first I have to talk about inflammation”

Niacin as a treatment for covid? (Probably no, but I’m glad we’re checking)

Introduction This article contains an interview with a doctor who believes NAD+ is the secret to covid’s heavy morbidity and mortality toll. The description was unusually well done for internet crackpottery. This is hard to convey rigorously, but it had a mechanistic-ness and the right level of complexity about it, and it made the right … Continue reading “Niacin as a treatment for covid? (Probably no, but I’m glad we’re checking)”

Epistemic Spot Check: The Tapping Solution (Nick Ortner)

This is part of a series called epistemic spot checks, in which I investigate claims a book makes to see if it’s worth paying attention to, without attempting to be comprehensive about it. Introduction This is a weird review to write.  I went into reading The Tapping Solution with two beliefs: The scientific claims would be … Continue reading “Epistemic Spot Check: The Tapping Solution (Nick Ortner)”

Epistemic Spot Check: Full Catastrophe Living (Jon Kabat-Zinn)

Full Catastrophe Living is a little weird, because between the first edition and the second a lot of science came out testing the thesis.  For this blog post, I’m reviewing the new, scienced-up edition of FCL.  However I have ordered the older edition of the book (thanks, Patreon supporters and and have dreams of reviewing that … Continue reading “Epistemic Spot Check: Full Catastrophe Living (Jon Kabat-Zinn)”

Epistemic Spot Check: A Guide To Better Movement (Todd Hargrove)

Edit 7/20/17: See comments from the author about this review.  In particular, he believes I overstated his claims, sometimes by a lot.   This is part of an ongoing series assessing where the epistemic bar should be for self-help books. Introduction Thesis: increasing your physical capabilities is more often a matter of teaching your neurological system … Continue reading “Epistemic Spot Check: A Guide To Better Movement (Todd Hargrove)”

Epistemic Spot Check: Sapiens (Yuval Noah Harari)

Usually I try to write full reviews and only on things I recommend, because take downs are easy and there’s enough negativity in the world.  But a few people on facebook expressed interest in having me factcheck early chapters in books, so they could know what was worth trying.  This is my test of that. … Continue reading “Epistemic Spot Check: Sapiens (Yuval Noah Harari)”

Xylitol for sinusitis

I’m taking on sinus inflammation because it’s a major contributor to my motion sickness, which is a major contributor to making commuting suck, and commuting is one of very few things that can actually depress your hedonic set point (psychologist talk for “make you miserable”).  My doctor has suggested xylitol nasal spray, which she claims inhibits irritation … Continue reading “Xylitol for sinusitis”

Prostaglandin, omega-3s, and health

My cat has lost weight since going on a special “I’m inbred and my kidneys don’t want to kidney” diet.  He’s also wheezing a lot.  My vet has recommended fish oil to get him some extra calories, and to fight the wheezing, if the wheezing is something something allergy something something prostaglandin.  She didn’t explain … Continue reading “Prostaglandin, omega-3s, and health”