Luck Based Medicine: No Good Very Bad Winter Cured My Hypothyroidism

I’ve previously written about Luck Based Medicine: the idea that, having exhausted all the reasonable cures for some issue, you are better off just trying shit rather than trying to reason more cures into existence. I share LBM success stories primarily as propaganda for the concept: the chance any one cure works for anyone else is <10% (sometimes much less), but a culture where people try things and share their results.

I’ve also previously written about my Very Unlucky Winter. My mattress developed mold, and in the course of three months I had four distinct respiratory infections, to devastating effect. A year later I am still working my way through side effects like asthma and foot pain. 

But, uh, I also appear to have cured my hypothyroidism, and the best hypothesis as to why is all the povidone iodine I gargled for all those respiratory infections illnesses.

Usually when I discuss fringe medicine I like to say “anything with a real effect can hurt you”, because it’s a nice catchall for potential danger. In this case, I can be more direct: anything that cures hypothyroidism has a risk of causing hyperthyroidism. The symptoms for this start with “very annoying” and end at “permanent disability or death”, so if you’re going to try iodine, it absolutely needs to be under medical supervision with regular testing. 

All that said…

I was first diagnosed with hypothyroidism 15 years ago, and 10 years ago tried titrating off medication but was forced back on. My thyroid numbers were in the range where mainstream MDs would think about treating and every ND, NP, or integrative MD would treat immediately. 

Low iodine can contribute to hypothyroidism, and my serum iodine tested at low normal for years, so we had of course tried supplementing iodine via pills, repeatedly, to no result. No change in thyroid and no change in serum iodine levels.

In January of the Very Unlucky Winter, I caught covid. I take covid hard under the best of circumstances and was still suffering aftereffects from RSV the previous month, so I was quite scared. Reddit suggested gargling povidone iodine and after irresponsibly little research, I tried it. My irresponsibility paid off in that the covid case was short and didn’t reach my lungs. I stopped taking iodine when I recovered but between all the illnesses, potential illnesses, and prophylactic use I ened up using it for quite a long period.

My memories of this time are very fuzzy and there were a lot of things going on, but the important bits are: I developed terrible insomnia, hand tremors, and temperature regulation issues. These had multiple potential explanations, but one of them was hyperthyroidism so my doctor had me tested. Sure enough, I had healed my thyroid to the point my once-necessary medication was giving me hyperthyroidism. 

Over the next few months I continued gargling with iodine and titrating my medication down. After ~6 months I was off it entirely. I’ve since been retested twice (6 weeks and 20 weeks after ceasing medication) and it looks like I’m clean. 

Could this have been caused by something besides iodine? I suppose, and I was on a fantastic number of pills, but I can’t figure out what else it could be. Hypothyroidism has a very short list of curable underlying causes, and none of them are treated by anything I was taking. 

So why did gargling iodine work when pills didn’t? It could be the formulation, but given my digestive system’s deepseated issues, I’m suspicious that the key was letting the iodine be absorbed through the mucous membrane of the throat, rather than attempting to through the gut. If that’s true, maybe I can work around my other unresponsive vitamin deficiencies by using sublingual multivitamins. I started them in June and am waiting to take the relevant test.

Thank you to my Patreon patrons for their support of this work. 

There is a $500 bounty for reporting errors that cause me to change my beliefs, and an at-my-discretion bounty for smaller errors. 

7 thoughts on “Luck Based Medicine: No Good Very Bad Winter Cured My Hypothyroidism”

  1. Do you have a rough idea how frequently you were gargling with the iodone? Were you using the .5% Betadine gargle? I have been using it this winter at first sign of a sore throat (otherwise using CPC mouthwash 2-3x daily), which has been more frequent than I expected so far. I’ve managed to avoid illnesses that my kids brought home 2 or 3 times, but that streak may be about to come to an end.

    1. Yes, 0.5% betadine.

      When I was using it to treat illness it was 5-8 times per day, when it was just for thyroid it was 1 time per day. Ballpark I spent 3 months out of 7 on the heavier dose.

      1. Thanks. Was that three months straight or broken up over the 7 the months?

        I forgot to mention I’ve been using Enovid as well (also at first sign of illness or when kids get sick, rather than continuously). Both 3-4 times a day when in use. I’ve probably had four or five 3-7 day stretches of use since September. I’ll come back in late spring and let you know how the winter turned out.

        Since I have no underlying thyroid condition, it seems like transient hypothyroidism is the likeliest issue I would have with the Betadine. I will keep an eye out for any of those type of symptoms.

      2. Great, thanks for clarifying. The following is cribbed from Claude, so verify before taking any action, but the Wolff-Chaikoff effect is apparently when the body temporarily reduces its production of thyroid hormone in the presence of iodine. In people with a normal functioning thyroid, this results in a temporary mild hypothyroidism that resolves shortly after the iodine goes away. 

        In people with underlying thyroid condition (either hypo or hyper), the effect is more unpredictable and the Jod-Basedow effect can result in hyperthyroidism. 

  2. Thanks for your writings, the first LBM article really hits home as yet another chronically fatigued woman, with many of the common suspects in the IACC constellation. I don’t care how I get to feeling better.

    It seems likely mucosal absorption of iodine was causal here, but I was just curious if any of those pills happened to include selenium?

    I wondered if you might have been (¿additionally?) selenium deficient given your prior digestive troubles. Schomburg et al.’s work suggests avoiding selenium deficiency is critical in the autoimmune thyroiditis risk populations since they’re necessary for the deiodinases for eventual thyroid hormone utilization. Conversely, impaired iodine absorption with normal/high selenium could suggest iodine wasting.

    Prof. Lutz Schomburg, MD New Autoantibodies in ME/CFS — 2024 August 8, Invest in ME Research – International 16th ME Conference 2024 https://youtu.be/Th2Q44V_Pjg

    Sun Q, Oltra E, Dijck-Brouwer DAJ, Chillon TS, Seemann P, Asaad S, Demircan K, Espejo-Oltra JA, Sánchez-Fito T, Martín-Martínez E, Minich WB, Muskiet FAJ, Schomburg L. Autoantibodies to selenoprotein P in chronic fatigue syndrome suggest selenium transport impairment and acquired resistance to thyroid hormone. Redox Biol. 2023 Sep;65:102796. https://doi.org/10.1016%2Fj.redox.2023.102796

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